Holmium Laser Enucleation of the Prostate (HoLEP) vs Transurethral Resection of the Prostate (TURP) for Large Prostate Glands (40-200g)
Gilling P, Kennett K, Fraundorfer M

INTRODUCTION: Holmium Laser Enucleation of the Prostate (HoLEP) is a transurethral procedure to enucleate the adenomatous prostate in a retrograde direction, using the Holmium laser (2140nm) as the energy source. Theadenoma is retrieved from the bladder using a mechanical tissue morcellator. This procedure is compared to Transurethral Electrocautery resection of the Prostate (TURP) in a randomized trial comparing outcomes in patients with ultrasound prostate volumes of 40-200ml. The data is complete to 1 month, follow-up is ongoing.

SUMMARY: -HoLEP & morcellation is compared to TURP in large glands (40-200ml TRUS volume) -60 patients were randomized (well-matched groups) -HoLEP took longer to perform but more tissue was removed -HoLEP was more efficient in removing tissue compared to TURP but morcellation was much slower than tissue evacuation following TURP -There was a shorter hospital and catheter time and fewer adverse events with HoLEP -Pressure-flow studies and TRUS volumes favored HoLEP at 6 months -Symptoms and flow rates are similar to 1 year, but data is not complete

Poster Presentation at the XVth Congress of the Geneva EAU April 7th, 2001

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